A new approach to control the enigmatic activity of aldose reductase.

A new approach to control the enigmatic activity of aldose reductase.

Aldose reductase (AR) is an NADPH-dependent reductase, which acts on a variety of hydrophilic as well as hydrophobic aldehydes. It is currently defined as the first enzyme in the so-called polyol pathway, in which glucose is transformed into sorbitol by AR and then to fructose by an NAD(+)-dependent...

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Bibliographic Details
Main Authors: Antonella Del-Corso, Francesco Balestri, Elisa Di Bugno, Roberta Moschini, Mario Cappiello, Stefania Sartini, Concettina La-Motta, Federico Da-Settimo, Umberto Mura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24019949/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24019949/?tool=EBI

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