Targeting the NCOA3-SP1-TERT axis for tumor growth in hepatocellular carcinoma

Targeting the NCOA3-SP1-TERT axis for tumor growth in hepatocellular carcinoma

Abstract Hepatocellular carcinoma (HCC) has a high mortality rate and lacks an effective therapeutic target. Elevated expression of human telomerase reverse transcriptase (TERT) is an important hallmark in cancers, but the mechanism by which TERT is activated differentially in cancers is poorly unde...

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Bibliographic Details
Main Authors: Wenbin Li, Yue Yan, Zongheng Zheng, Qiaohua Zhu, Qian Long, Silei Sui, Meihua Luo, Miao Chen, Yizhuo Li, Yijun Hua, Wuguo Deng, Renchun Lai, Liren Li
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03218-x

Internet

https://doi.org/10.1038/s41419-020-03218-x

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