Notch2 Is Required for Inflammatory Cytokine-Driven Goblet Cell Metaplasia in the Lung

Notch2 Is Required for Inflammatory Cytokine-Driven Goblet Cell Metaplasia in the Lung

The balance and distribution of epithelial cell types is required to maintain tissue homeostasis. A hallmark of airway diseases is epithelial remodeling, leading to increased goblet cell numbers and an overproduction of mucus. In the conducting airway, basal cells act as progenitors for both secreto...

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Bibliographic Details
Main Authors: Henry Danahay, Angelica D. Pessotti, Julie Coote, Brooke E. Montgomery, Donghui Xia, Aaron Wilson, Haidi Yang, Zhao Wang, Luke Bevan, Chris Thomas, Stephanie Petit, Anne London, Peter LeMotte, Arno Doelemeyer, Germán L. Vélez-Reyes, Paula Bernasconi, Christy J. Fryer, Matt Edwards, Paola Capodieci, Amy Chen, Marc Hild, Aron B. Jaffe
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714010468

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http://www.sciencedirect.com/science/article/pii/S2211124714010468

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