Gut microbiota from coronary artery disease patients contributes to vascular dysfunction in mice by regulating bile acid metabolism and immune activation

Gut microbiota from coronary artery disease patients contributes to vascular dysfunction in mice by regulating bile acid metabolism and immune activation

Abstract Background The gut microbiota was shown to play a crucial role in the development of vascular dysfunction, and the bacterial composition differed between healthy controls and coronary artery disease patients. The goal of this study was to investigate how the gut microbiota affects host meta...

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Bibliographic Details
Main Authors: Honghong Liu, Ran Tian, Hui Wang, Siqin Feng, Hanyu Li, Ying Xiao, Xiaodong Luan, Zhiyu Zhang, Na Shi, Haitao Niu, Shuyang Zhang
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Translational Medicine
Subjects:
Gut microbiota
Faecal microbiota transplantation
Bile acids
Intestinal immunity
Vascular dysfunction
Online Access:http://link.springer.com/article/10.1186/s12967-020-02539-x

Internet

http://link.springer.com/article/10.1186/s12967-020-02539-x

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