Chromatin regulation in schistosomes and histone modifying enzymes as drug targets

Only one drug is currently available for the treatment and control of schistosomiasis and the increasing risk of selecting strains of schistosome that are resistant to praziquantel means that the development of new drugs is urgent. With this objective we have chosen to target the enzymes modifying h...

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Bibliographic Details
Main Authors: Raymond John Pierce, Florence Dubois-Abdesselem, Stéphanie Caby, Jacques Trolet, Julien Lancelot, Frédérik Oger, Nicolas Bertheaume, Emmanuel Roger
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2011-11-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000700003&lng=en&tlng=en