Galectin-9 Alleviates LPS-Induced Preeclampsia-Like Impairment in Rats via Switching Decidual Macrophage Polarization to M2 Subtype

Galectin-9 Alleviates LPS-Induced Preeclampsia-Like Impairment in Rats via Switching Decidual Macrophage Polarization to M2 Subtype

Dysfunction of decidual macrophages (DMs) is considered a critical event in the pathogenesis of pre-eclampsia (PE). T cell immunoglobulin mucin 3 (Tim-3) is an important negative regulatory molecule that induces immune tolerance by interacting with its ligand Galectin-9 (Gal-9) and thus modulating f...

Full description

Bibliographic Details
Main Authors: Zhi-Hui Li, Li-Ling Wang, Hong Liu, Kahinho P. Muyayalo, Xiao-Bo Huang, Gil Mor, Ai-Hua Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
Galectin-9
Tim-3
pre-eclampsia
decidual macrophage
polarization
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03142/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.03142/full

Similar Items