mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice

mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice

Energy dissipation through interscapular brown adipose tissue (iBAT) thermogenesis is an important contributor to adaptive energy expenditure. However, it remains unresolved how acute and chronic changes in energy availability are detected by the brain to adjust iBAT activity and maintain energy hom...

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Bibliographic Details
Main Authors: Luke K Burke, Tamana Darwish, Althea R Cavanaugh, Sam Virtue, Emma Roth, Joanna Morro, Shun-Mei Liu, Jing Xia, Jeffrey W Dalley, Keith Burling, Streamson Chua, Toni Vidal-Puig, Gary J Schwartz, Clémence Blouet
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-05-01
Series:eLife
Subjects:
obesity
hypothalamus
energy expenditure
brown fat
nutrient-sensing
mTORC1
Online Access:https://elifesciences.org/articles/22848

Internet

https://elifesciences.org/articles/22848

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