Impaired growth and force production in skeletal muscles of young partially pancreatectomized rats: a model of adolescent type 1 diabetic myopathy?

This present study investigated the temporal effects of type 1 diabetes mellitus (T1DM) on adolescent skeletal muscle growth, morphology and contractile properties using a 90% partial pancreatecomy (Px) model of the disease. Four week-old male Sprague-Dawley rats were randomly assigned to Px (n = 25...

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Bibliographic Details
Main Authors: Carly S Gordon, Antonio S Serino, Matthew P Krause, Jonathan E Campbell, Enzo Cafarelli, Olasunkanmi A J Adegoke, Thomas J Hawke, Michael C Riddell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2984438?pdf=render