Effects of Antimalarial Tafenoquine on Blood Platelet Activity and Survival

Effects of Antimalarial Tafenoquine on Blood Platelet Activity and Survival

Background/Aims: The 8-aminoquinoline tafenoquine has been shown to be effective against Plasmodia, Leishmania and Trypanosoma. The substance is at least in part effective by triggering apoptosis of the parasites. Moreover, tafenoquine has been shown to trigger eryptosis, the suicidal erythrocyte de...

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Bibliographic Details
Main Authors: Hang Cao, Rosi Bissinger, Anja T. Umbach, Abdulla Al Mamun Bhuyan, Florian Lang, Meinrad Gawaz
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cytosolic Ca2+ concentration
P-selectin
Integrin
Caspase
Cell volume
Phosphatidylserine translocation
Online Access:http://www.karger.com/Article/FullText/456319

Internet

http://www.karger.com/Article/FullText/456319

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