Effect of Buspirone, Fluoxetine and 8-OH-DPAT on Striatal Expression of Bax, Caspase-3 and Bcl-2 Proteins in 6-Hydroxydopamine-Induced Hemi-Parkinsonian Rats

Purpose: The exact pathogenesis of sporadic parkinson’s disease (PD) is still unclear. Numerous evidences suggest involvement of apoptosis in the death of dopaminergic neurons. In this study we investigated the effect of sub-chronic administration of buspirone, fluoxetine and 8-hydroxy-2-[di-n-propy...

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Bibliographic Details
Main Authors: Hamdollah Sharifi, Alireza Nayebi, Safar Farajnia, Rasool Haddadi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2015-11-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-5-491.pdf