A one-year prospective, randomized, placebo-controlled, quadruple-blinded, phase II safety pilot trial of combination therapy with interferon beta-1a and mycophenolate mofetil in early relapsing—remitting multiple sclerosis (TIME MS)

A one-year prospective, randomized, placebo-controlled, quadruple-blinded, phase II safety pilot trial of combination therapy with interferon beta-1a and mycophenolate mofetil in early relapsing—remitting multiple sclerosis (TIME MS)

Background: Mycophenolate mofetil (MMF) is an oral DNA base synthesis inhibitor with immunomodulatory effects on B cells, T cells, and macrophages. Objective: To conduct a safety and tolerability pilot study of interferon beta-1a (IFN-b1a) in combination with either placebo or oral MMF in multiple s...

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Bibliographic Details
Main Authors: Gina M. Remington, Katherine Treadaway, Teresa Frohman, Amber Salter, Olaf Stüve, Michael K. Racke, Kathleen Hawker, Federica Agosta, Maria Pia Sormani, Massimo Filippi, Elliot M. Frohman
Format: Article
Language:English
Published: SAGE Publishing 2010-01-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756285609355851

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https://doi.org/10.1177/1756285609355851

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