Immunogenicity of Protein Therapeutics: A Lymph Node Perspective

The continuous development of molecular biology and protein engineering technologies enables the expansion of the breadth and complexity of protein therapeutics for in vivo administration. However, the immunogenicity and associated in vivo development of antibodies against therapeutics are a major r...

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Bibliographic Details
Main Authors: Kristy Fu, Kylie March, Aikaterini Alexaki, Giulia Fabozzi, Eirini Moysi, Constantinos Petrovas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
ADA
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00791/full