Decreased PEDF Promotes Hepatic Fatty Acid Uptake and Lipid Droplet Formation in the Pathogenesis of NAFLD

Non-alcoholic fatty liver disease (NAFLD), the leading cause of chronic liver diseases worldwide, ranges from simple steatosis to steatohepatitis, with the risk for progressive fibrosis or even cirrhosis. While simple steatosis is a relatively benign condition, the buildup of toxic lipid metabolites...

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Bibliographic Details
Main Authors: Kuang-Tzu Huang, Kuang-Den Chen, Li-Wen Hsu, Chao-Pin Kung, Shu-Rong Li, Chien-Chih Chen, King-Wah Chiu, Shigeru Goto, Chao-Long Chen
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/12/1/270