The endogenous preproglucagon system is not essential for gut growth homeostasis in mice

The endogenous preproglucagon system is not essential for gut growth homeostasis in mice

Objective: The prevalence of obesity and related co-morbidities is reaching pandemic proportions. Today, the most effective obesity treatments are glucagon-like peptide 1 (GLP-1) analogs and bariatric surgery. Interestingly, both intervention paradigms have been associated with adaptive growth respo...

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Bibliographic Details
Main Authors: Pernille Wismann, Pernille Barkholt, Thomas Secher, Niels Vrang, Henrik B. Hansen, Palle Bekker Jeppesen, Laurie L. Baggio, Jacqueline A. Koehler, Daniel J. Drucker, Darleen A. Sandoval, Jacob Jelsing
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Molecular Metabolism
Subjects:
GLP-1R
GLP-2R
GCG
Preproglucagon
Intestinal volume
Obesity
Diabetes
Bariatric surgery
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817302260

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http://www.sciencedirect.com/science/article/pii/S2212877817302260

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