Leptin Receptors in RIP-Cre25Mgn Neurons Mediate Anti-dyslipidemia Effects of Leptin in Insulin-Deficient Mice

Leptin Receptors in RIP-Cre25Mgn Neurons Mediate Anti-dyslipidemia Effects of Leptin in Insulin-Deficient Mice

Leptin is a potent endocrine hormone produced by adipose tissue and regulates a broad range of whole-body metabolism such as glucose and lipid metabolism, even without insulin. Central leptin signaling can lower hyperglycemia in insulin-deficient rodents via multiple mechanisms, including improvemen...

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Bibliographic Details
Main Authors: Ashish Singha, Juan Pablo Palavicini, Meixia Pan, Scotlynn Farmer, Darleen Sandoval, Xianlin Han, Teppei Fujikawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Endocrinology
Subjects:
leptin
insulin deficiency
the hypothalamus
glucose metabolism
lipid metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.588447/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.588447/full

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