Involvement of MET/TWIST/APC Combination or the Potential Role of Ossification Factors in Pediatric High-Grade Osteosarcoma Oncogenesis

Involvement of MET/TWIST/APC Combination or the Potential Role of Ossification Factors in Pediatric High-Grade Osteosarcoma Oncogenesis

Dysregulated cell growth or differentiation due to misexpression of developmental critical factors seems to be a decisive event in oncogenesis. As osteosarcomas are histologically defined by malignant osteoblasts producing an osteoid component, we prospected in pediatric osteosarcomas treated with...

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Bibliographic Details
Main Authors: Natacha Entz-Werle, Thomas Lavaux, Nadia Metzger, Corinne Stoetzel, Christelle Lasthaus, Perrine Marec, Chantal Kalita, Laurence Brugieres, Helene Pacquement, Claudine Schmitt, Marie-Dominique Tabone, Jean-Claude Gentet, Patrick Lutz, Annie Babin, Pierre Oudet, Marie Pierre Gaub, Fabienne Perrin-Schmitt
Format: Article
Language:English
Published: Elsevier 2007-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Pediatric osteosarcoma
osteogenesis
TWIST
APC
MET
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800753

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http://www.sciencedirect.com/science/article/pii/S1476558607800753

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