Soluble AXL: a possible circulating biomarker for neurofibromatosis type 1 related tumor burden.

Neurofibromatosis type 1 (NF1) is the most common tumor predisposition disorder affecting 1/3500 worldwide. Patients are at risk of developing benign (neurofibromas) and malignant peripheral nerve sheath tumors (MPNST). The AXL receptor tyrosine kinase has been implicated in several kinds of cancers...

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Bibliographic Details
Main Authors: Gunnar Johansson, Po-Chun Peng, Po-Yuan Huang, Hsiung-Fei Chien, Kuo-Tai Hua, Min-Liang Kuo, Chin-Tin Chen, Ming-Jen Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4281253?pdf=render