HspB4/αA-Crystallin Modulates Neuroinflammation in the Retina via the Stress-Specific Inflammatory Pathways

HspB4/αA-Crystallin Modulates Neuroinflammation in the Retina via the Stress-Specific Inflammatory Pathways

Purpose: We have previously demonstrated that HspB4/αA-crystallin, a molecular chaperone, plays an important intrinsic neuroprotective role during diabetes, by its phosphorylation on residue 148. We also reported that HspB4/αA-crystallin is highly expressed by glial cells. There is a growing interes...

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Bibliographic Details
Main Authors: Madhu Nath, Yang Shan, Angela M. Myers, Patrice Elie Fort
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Journal of Clinical Medicine
Subjects:
αA-crystallin
Müller glial cells
NF-kB
metabolic stress
inflammatory markers
Online Access:https://www.mdpi.com/2077-0383/10/11/2384

Internet

https://www.mdpi.com/2077-0383/10/11/2384

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