Genomic and Geographic Context for the Evolution of High-Risk Carbapenem-Resistant Enterobacter cloacae Complex Clones ST171 and ST78

Genomic and Geographic Context for the Evolution of High-Risk Carbapenem-Resistant Enterobacter cloacae Complex Clones ST171 and ST78

Recent reports have established the escalating threat of carbapenem-resistant Enterobacter cloacae complex (CREC). Here, we demonstrate that CREC has evolved as a highly antibiotic-resistant rather than highly virulent nosocomial pathogen. Applying genomics and Bayesian phylogenetic analyses to a 7-...

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Bibliographic Details
Main Authors: Angela Gomez-Simmonds, Medini K. Annavajhala, Zheng Wang, Nenad Macesic, Yue Hu, Marla J. Giddins, Aidan O’Malley, Nora C. Toussaint, Susan Whittier, Victor J. Torres, Anne-Catrin Uhlemann
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mBio
Subjects:
antimicrobial resistance
bacterial evolution
bacterial genomics
carbapenem resistance
Enterobacter cloacae
Online Access:https://doi.org/10.1128/mBio.00542-18

Internet

https://doi.org/10.1128/mBio.00542-18

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