A genome-wide scan statistic framework for whole-genome sequence data analysis

Whole-genome sequencing data reveals a large number of variants for testing their associations with phenotypic traits and diseases. Here, the authors develop WGScan, a statistical method for detecting the existence and estimating the locations of the association signal at genome-wide scale.

Bibliographic Details
Main Authors: Zihuai He, Bin Xu, Joseph Buxbaum, Iuliana Ionita-Laza
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11023-0