Potent anti-tumor immunostimulatory biocompatible nanohydrogel made from DNA

Potent anti-tumor immunostimulatory biocompatible nanohydrogel made from DNA

Abstract Unmethylated CpG oligodeoxynucleotides are potent immunostimulatory motifs in activating both innate and acquired immune system by inducing Th1 type antigen-specific T cell responses, but their instability in serum greatly influences their immunostimulant efficiency. Here, we constructed a...

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Bibliographic Details
Main Authors: Jiana Jiang, Xianming Kong, Yuexia Xie, Hanbing Zou, Qianyun Tang, Ding Ma, Xue Zhao, Xiaozhen He, Anyue Xia, Peifeng Liu
Format: Article
Language:English
Published: SpringerOpen 2019-06-01
Series:Nanoscale Research Letters
Subjects:
CpG
Nanohydrogel
Immunotherapy
Macrophage
Glioma
Online Access:http://link.springer.com/article/10.1186/s11671-019-3032-9

Internet

http://link.springer.com/article/10.1186/s11671-019-3032-9

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