Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex

Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex

Herpesviruses acquire their membrane envelopes in the cytoplasm of infected cells via a molecular mechanism that remains unclear. Herpes simplex virus (HSV)−1 proteins pUL7 and pUL51 form a complex required for efficient virus envelopment. We show that interaction between homologues of pUL7 and pUL5...

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Bibliographic Details
Main Authors: Benjamin G Butt, Danielle J Owen, Cy M Jeffries, Lyudmila Ivanova, Chris H Hill, Jack W Houghton, Md Firoz Ahmed, Robin Antrobus, Dmitri I Svergun, John J Welch, Colin M Crump, Stephen C Graham
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
small-angle X-ray scattering (SAXS)
secondary envelopment
virus budding
focal adhesions
human cytomegalovirus (hcmv)
Online Access:https://elifesciences.org/articles/53789

Internet

https://elifesciences.org/articles/53789

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