The Effects of pH and Excipients on Exenatide Stability in Solution

The Effects of pH and Excipients on Exenatide Stability in Solution

Exenatide, a glucagon-like peptide-1 receptor agonist, is the active pharmaceutical ingredient in Byetta<sup>®</sup> and Bydureon<sup>®</sup>, two type 2 diabetes drug products that have generics and multiple follow-up formulations currently in development. Even though exenat...

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Bibliographic Details
Main Authors: Alexander Benet, Troy Halseth, Jukyung Kang, April Kim, Rose Ackermann, Santhanakrishnan Srinivasan, Steven Schwendeman, Anna Schwendeman
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
exenatide
generic peptides
GLP1 agonists
diabetes
analytical characterization
physical/chemical degradation
Online Access:https://www.mdpi.com/1999-4923/13/8/1263

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https://www.mdpi.com/1999-4923/13/8/1263

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