Microsatellite tandem repeats are abundant in human promoters and are associated with regulatory elements.

Tandem repeats are genomic elements that are prone to changes in repeat number and are thus often polymorphic. These sequences are found at a high density at the start of human genes, in the gene's promoter. Increasing empirical evidence suggests that length variation in these tandem repeats ca...

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Bibliographic Details
Main Authors: Sterling Sawaya, Andrew Bagshaw, Emmanuel Buschiazzo, Pankaj Kumar, Shantanu Chowdhury, Michael A Black, Neil Gemmell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3566118?pdf=render