Antidepressant-like effect of lead in adult mice

It has been reported that lead can cause behavioral impairment by inhibiting the N-methyl-D-aspartate (NMDA) receptor complex. MK-801, a noncompetitive NMDA receptor antagonist, exhibits an antidepressant-like action in the forced swimming test. The purpose of the present study was to determine whet...

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Bibliographic Details
Main Authors: M. Mantovani, A.S. Matteussi, A.L.S. Rodrigues
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1999-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001200017