Immunogenicity of the Plasmodium falciparum PfEMP1-VarO Adhesin: Induction of Surface-Reactive and Rosette-Disrupting Antibodies to VarO Infected Erythrocytes.

Immunogenicity of the Plasmodium falciparum PfEMP1-VarO Adhesin: Induction of Surface-Reactive and Rosette-Disrupting Antibodies to VarO Infected Erythrocytes.

Adhesion of Plasmodium falciparum-infected red blood cells (iRBC) to human erythrocytes (i.e. rosetting) is associated with severe malaria. Rosetting results from interactions between a subset of variant PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1) adhesins and specific erythrocyte...

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Bibliographic Details
Main Authors: Micheline Guillotte, Alexandre Juillerat, Sébastien Igonet, Audrey Hessel, Stéphane Petres, Elodie Crublet, Cécile Le Scanf, Anita Lewit-Bentley, Graham A Bentley, Inès Vigan-Womas, Odile Mercereau-Puijalon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4519321?pdf=render

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http://europepmc.org/articles/PMC4519321?pdf=render

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