Protective Efficacy of Inhaled BCG Vaccination Against Ultra-Low Dose Aerosol <i>M. tuberculosis</i> Challenge in Rhesus Macaques

Protective Efficacy of Inhaled BCG Vaccination Against Ultra-Low Dose Aerosol <i>M. tuberculosis</i> Challenge in Rhesus Macaques

Ten million cases of tuberculosis (TB) were reported in 2018 with a further 1.5 million deaths attributed to the disease. Improved vaccination strategies are urgently required to tackle the ongoing global TB epidemic. In the absence of a validated correlate of protection, highly characterised pre-cl...

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Bibliographic Details
Main Authors: Andrew D. White, Charlotte Sarfas, Laura S. Sibley, Jennie Gullick, Simon Clark, Emma Rayner, Fergus Gleeson, Martí Català, Isabel Nogueira, Pere-Joan Cardona, Cristina Vilaplana, Mike J. Dennis, Ann Williams, Sally A. Sharpe
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
tuberculosis
BCG
vaccine
non-human primate
macaque
aerosol vaccination
Online Access:https://www.mdpi.com/1999-4923/12/5/394

Internet

https://www.mdpi.com/1999-4923/12/5/394

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