OneArmPhaseTwoStudy: An R Package for Planning, Conducting, and Analysing Single-Arm Phase II Studies

OneArmPhaseTwoStudy: An R Package for Planning, Conducting, and Analysing Single-Arm Phase II Studies

In clinical phase II studies, the efficacy of a promising therapy is tested in patients for the first time. Based on the results, it is decided whether the development programme should be stopped or whether the benefit-risk profile is promising enough to justify the initiation of large phase III stu...

Full description

Bibliographic Details
Main Authors: Meinhard Kieser, Marius Wirths, Stefan Englert, Cornelia Ursula Kunz, Geraldine Rauch
Format: Article
Language:English
Published: Foundation for Open Access Statistics 2017-11-01
Series:Journal of Statistical Software
Subjects:
clinical trial
single-arm study
two-stage design
binary data
exact method
adaptive design
Online Access:https://www.jstatsoft.org/index.php/jss/article/view/2457

Internet

https://www.jstatsoft.org/index.php/jss/article/view/2457

Similar Items