The Vav GEF Family: An Evolutionary and Functional Perspective
Vav proteins play roles as guanosine nucleotide exchange factors for Rho GTPases and signaling adaptors downstream of protein tyrosine kinases. The recent sequencing of the genomes of many species has revealed that this protein family originated in choanozoans, a group of unicellular organisms from...
Main Authors: | Sonia Rodríguez-Fdez, Xosé R. Bustelo |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/8/5/465 |
Similar Items
-
Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes
by: Sonia Rodríguez-Fdez, et al.
Published: (2020-03-01) -
Deoxyguanosine triphosphate, a possible target for reactive oxygen species-induced mutagenesis
by: Tassotto, Mary Lynn Benka
Published: (2012) -
Studies on enzymes involved in the biosynthesis of pterin cofactors
by: Baker, Stephen John
Published: (1997) -
RhoB regulates cell migration through altered focal adhesion dynamics
by: Francisco M. Vega, et al.
Published: (2012-01-01) -
PDGF-induced cell motility depends on EDG-1
by: Terry Peter, et al.
Published: (2001-03-01)