Argonaute (AGO) proteins play an essential role in mediating BMP9-induced osteogenic signaling in mesenchymal stem cells (MSCs)

Argonaute (AGO) proteins play an essential role in mediating BMP9-induced osteogenic signaling in mesenchymal stem cells (MSCs)

As multipotent progenitor cells, mesenchymal stem cells (MSCs) can renew themselves and give rise to multiple lineages including osteoblastic, chondrogenic and adipogenic lineages. It's previously shown that BMP9 is the most potent BMP and induces osteogenic and adipogenic differentiation of MS...

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Bibliographic Details
Main Authors: Yukun Mao, Na Ni, Linjuan Huang, Jiaming Fan, Hao Wang, Fang He, Qing Liu, Deyao Shi, Kai Fu, Mikhail Pakvasa, William Wagstaff, Andrew Blake Tucker, Connie Chen, Russell R. Reid, Rex C. Haydon, Sherwin H. Ho, Michael J. Lee, Tong-Chuan He, Jian Yang, Le Shen, Lin Cai, Hue H. Luu
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Genes and Diseases
Subjects:
Argonaute (AGO) proteins
BMP9
Bone formation
Lineage-specific differentiation
Mesenchymal stem cells
miRNA biogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304221000581

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http://www.sciencedirect.com/science/article/pii/S2352304221000581

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