Biosynthetic Pathways and the Role of the Mas Receptor in the Effects of Angiotensin-(1–7) in Smooth Muscles

Ang-(1–7) is produced via degradation of Ang II by the human angiotensin converting enzyme, also known as ACE2. In the cardiovascular system, Ang-(1–7) has been shown to produce effects that are opposite to those of Ang II. These include smooth muscle relaxation and cardioprotection. While the roles...

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Bibliographic Details
Main Authors: Marcio Augusto Fressatto de Godoy, Larissa Pernomian, Ana Maria de Oliveira, Satish Rattan
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2012/121740