Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension

Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension

The lymphatic vasculature is involved in the pathogenesis of acute cardiac injuries, but little is known about its role in chronic cardiac dysfunction. Here, we demonstrate that angiotensin II infusion induced cardiac inflammation and fibrosis at 1 week and caused cardiac dysfunction and impaired ly...

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Bibliographic Details
Main Authors: LouJin Song, Xian Chen, Terri A Swanson, Brianna LaViolette, Jincheng Pang, Teresa Cunio, Michael W Nagle, Shoh Asano, Katherine Hales, Arun Shipstone, Hanna Sobon, Sabra D Al-Harthy, Youngwook Ahn, Steven Kreuser, Andrew Robertson, Casey Ritenour, Frank Voigt, Magalie Boucher, Furong Sun, William C Sessa, Rachel J Roth Flach
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
lymphatic
endothelial
cardiac dysfunction
inflammation
hypertension
fibrosis
Online Access:https://elifesciences.org/articles/58376

Internet

https://elifesciences.org/articles/58376

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