The Effect of Signal Sequence and His-tags on the Expression and Anti-Thrombin Activity of Recombinant Hirudin

Background:       Adding signal sequence and His- tags to the expression vectors of recombinant proteins usually increased the production yield by promoting protein secretion to the periplasmic space and by facilitating the purification processes. In this study, three different expressio...

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Bibliographic Details
Main Authors: Shahin Hadadian, Leila Pishkar, Elmira kazemi, Saeme Asgari, Mina Sepahi, Samira Komijani, Parviz Afrough, Nazanin Mohajerani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2021-06-01
Series:Journal of Medical Bacteriology
Subjects:
Online Access:https://jmb.tums.ac.ir/index.php/jmb/article/view/428