Enantiomeric Separation of Tramadol and Its Metabolites: Method Validation and Application to Environmental Samples

Enantiomeric Separation of Tramadol and Its Metabolites: Method Validation and Application to Environmental Samples

The accurate assessment of racemic pharmaceuticals requires enantioselective analytical methods. This study presents the development and validation of an enantioselective liquid chromatography with a fluorescence detection method for the concomitant quantification of the enantiomers of tramadol and...

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Bibliographic Details
Main Authors: Cátia Silva, Cláudia Ribeiro, Alexandra S. Maia, Virgínia Gonçalves, Maria Elizabeth Tiritan, Carlos Afonso
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Symmetry
Subjects:
chiral pharmaceuticals
tramadol
N-desmethyltramadol
O-desmethyltramadol
wastewater
Lux Cellulose-4 column
Online Access:https://www.mdpi.com/2073-8994/9/9/170

Internet

https://www.mdpi.com/2073-8994/9/9/170

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