Bergenin Activates SIRT1 as a Novel Therapeutic Agent for Osteogenesis of Bone Mesenchymal Stem Cells

Bergenin Activates SIRT1 as a Novel Therapeutic Agent for Osteogenesis of Bone Mesenchymal Stem Cells

Bone mesenchymal stem cells (BMSCs) are important candidates for bone regeneration. The role of Bergenin, a C-glucoside of 4-O-methyl gallic acid obtained from the species, Bergenia, in BMSC osteogenesis has not yet been elucidated. We therefore investigated the effects of Bergenin on the osteogenes...

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Bibliographic Details
Main Authors: Weiduo Hou, Chenyi Ye, Mo Chen, Weixu Li, Xiang Gao, Rongxin He, Qiang Zheng, Wei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Pharmacology
Subjects:
Bergenin
bone mesenchymal stem cells
osteogenesis
SIRT1
bone regeneration
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00618/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00618/full

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