Effects of atorvastatin and metformin on development of pentylenetetrazole-induced seizure in mice

Recent studies have shown that statins and Metformin may have beneficial effects on seizure through different mechanisms. In the current study, we investigated whether Metformin, Atorvastatin, and concomitant uses of them have beneficial effects on pentylenetetrazole (PTZ)-induced kindling. Adult ma...

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Bibliographic Details
Main Authors: Mohammad Ali Zeyghami, Ebrahim Hesam, Parand Khadivar, Halimeh Khaton Hesam, Ali Ahmadnia, Abolfazl Amini
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402030606X