Notch Cooperates with Survivin to Maintain Stemness and to Stimulate Proliferation in Human Keratinocytes during Ageing

Notch Cooperates with Survivin to Maintain Stemness and to Stimulate Proliferation in Human Keratinocytes during Ageing

The Notch signaling pathway orchestrates cell fate by either inducing cell differentiation or maintaining cells in an undifferentiated state. This study aims to evaluate Notch expression and function in normal human keratinocytes. Notch1 is expressed in all epidermal layers, though to a different de...

Full description

Bibliographic Details
Main Authors: Elisabetta Palazzo, Paolo Morandi, Roberta Lotti, Annalisa Saltari, Francesca Truzzi, Sylvianne Schnebert, Marc Dumas, Alessandra Marconi, Carlo Pincelli
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:International Journal of Molecular Sciences
Subjects:
Notch1
survivin
keratinocytes
stem cells
Online Access:http://www.mdpi.com/1422-0067/16/11/25948

Internet

http://www.mdpi.com/1422-0067/16/11/25948

Similar Items