Diet-Dependent Changes of the DNA Methylome Using a Göttingen Minipig Model for Obesity

Diet-Dependent Changes of the DNA Methylome Using a Göttingen Minipig Model for Obesity

Objective: Environmental factors can influence obesity by epigenetic mechanisms. The aim of this study was to investigate obesity-related epigenetic changes and the potential for reversal of these changes in the liver of Göttingen minipigs subjected to diet interventions.Methods: High-throughput liq...

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Bibliographic Details
Main Authors: Y. Feng, S. Cirera, E. Taşöz, Y. Liu, L. H. Olsen, B. Ø. Christoffersen, H. D. Pedersen, T. P. Ludvigsen, R. K. Kirk, C. Schumacher-Petersen, Y. Deng, M. Fredholm, F. Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
epigenetics
promoter DNA methylation
diet intervention
obesity
metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.632859/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.632859/full

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