Integrated UPLC-Q/TOF-MS Technique and MALDI-MS to Study of the Efficacy of YiXinshu Capsules Against Heart Failure in a Rat Model

Integrated UPLC-Q/TOF-MS Technique and MALDI-MS to Study of the Efficacy of YiXinshu Capsules Against Heart Failure in a Rat Model

Background: Yixinshu Capsules (YXSC) are widely used in Chinese medicine for the treatment of cardiovascular diseases. However, the therapeutic mechanisms of action are not well understood.Method: In this study, a metabonomic approach based on integrated UPLC-Q/TOF-MS technique and MALDI-MS was util...

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Bibliographic Details
Main Authors: Jing Xu, Xianyu Li, Fangbo Zhang, Liying Tang, Junying Wei, Xiaoqing Lei, Huanhuan Wang, Yi Zhang, Defeng Li, Xuan Tang, Geng Li, Shihuan Tang, Hongwei Wu, Hongjun Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Pharmacology
Subjects:
heart failure
YiXinShu capsules
UPLC-Q/TOF-MS
MALDI-MS
metabonomic studies
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01474/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.01474/full

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