NBAS mutations cause acute liver failure: when acetaminophen is not a culprit

NBAS mutations cause acute liver failure: when acetaminophen is not a culprit

Abstract Background Pediatric acute-liver-failure due to acetaminophen (APAP) administration at therapeutic dosage is rare, while viral infections and metabolic defects are the prevalent causes. Yet, as acetaminophen is routinely used in febrile illnesses, it may be mistakenly held responsible for t...

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Bibliographic Details
Main Authors: Pier Luigi Calvo, Francesco Tandoi, Tobias B. Haak, Andrea Brunati, Michele Pinon, Dominic Dell Olio, Renato Romagnoli, Marco Spada
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Italian Journal of Pediatrics
Subjects:
Acute liver failure
Acetaminophen toxicity
N-Acetylcysteine
NBAS mutation
Liver Transplantation
Online Access:http://link.springer.com/article/10.1186/s13052-017-0406-4

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http://link.springer.com/article/10.1186/s13052-017-0406-4

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