Cognitive Changes in the Spinocerebellar Ataxias Due to Expanded Polyglutamine Tracts: A Survey of the Literature

The dominantly-inherited ataxias characterised by expanded polyglutamine tracts—spinocere bellar ataxias (SCAs) 1, 2, 3, 6, 7, 17, dentatorubral pallidoluysian atrophy (DRPLA) and, in part, SCA 8—have all been shown to result in various degrees of cognitive impairment. We survey the literature on t...

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Bibliographic Details
Main Authors: Evelyn Lindsay, Elsdon Storey
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/7/7/83