CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation

CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation

Microtubule (MT) nucleation is regulated by the γ-tubulin ring complex (γTuRC), conserved from yeast to humans. In Saccharomyces cerevisiae, γTuRC is composed of seven identical γ-tubulin small complex (γTuSC) sub-assemblies, which associate helically to template MT growth. γTuRC assembly provides a...

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Bibliographic Details
Main Authors: Axel F Brilot, Andrew S Lyon, Alex Zelter, Shruthi Viswanath, Alison Maxwell, Michael J MacCoss, Eric G Muller, Andrej Sali, Trisha N Davis, David A Agard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
microtubule nucleation
cytoskeleton
electron microscopy
Online Access:https://elifesciences.org/articles/65168

Internet

https://elifesciences.org/articles/65168

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