Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice[S]

Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice[S]

Lipogenesis in liver is highest in the postprandial state; insulin activates SREBP-1c, which transcriptionally activates genes involved in FA synthesis, whereas glucose activates carbohydrate-responsive element-binding protein (ChREBP), which activates both glycolysis and FA synthesis. Whether SREBP...

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Bibliographic Details
Main Authors: Albert G. Linden, Shili Li, Hwa Y. Choi, Fei Fang, Masashi Fukasawa, Kosaku Uyeda, Robert E. Hammer, Jay D. Horton, Luke J. Engelking, Guosheng Liang
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Lipid Research
Subjects:
carbohydrate-responsive element-binding protein
sterol regulatory element-binding protein -1c
adeno-associated virus
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520331369

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http://www.sciencedirect.com/science/article/pii/S0022227520331369

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