Wilms Tumor 1b Expression Defines a Pro-regenerative Macrophage Subtype and Is Required for Organ Regeneration in the Zebrafish

Summary: Organ regeneration is preceded by the recruitment of innate immune cells, which play an active role during repair and regrowth. Here, we studied macrophage subtypes during organ regeneration in the zebrafish, an animal model with a high regenerative capacity. We identified a macrophage subp...

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Bibliographic Details
Main Authors: Andrés Sanz-Morejón, Ana B. García-Redondo, Hanna Reuter, Inês J. Marques, Thomas Bates, María Galardi-Castilla, Andreas Große, Steffi Manig, Xavier Langa, Alexander Ernst, Indre Piragyte, Marius-Alexandru Botos, Juan Manuel González-Rosa, Marta Ruiz-Ortega, Ana M. Briones, Mercedes Salaices, Christoph Englert, Nadia Mercader
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471930871X