miR-449a induces EndMT, promotes the development of atherosclerosis by targeting the interaction between AdipoR2 and E-cadherin in Lipid Rafts

miR-449a induces EndMT, promotes the development of atherosclerosis by targeting the interaction between AdipoR2 and E-cadherin in Lipid Rafts

EndMT plays an important role in the relationship between endothelial dysfunction and atherosclerosis. This work will elucidate the biofunction induced by miR-449a and lipid rafts in EndMT and development of atherosclerosis. The differential miRNA expression between atherosclerotic plaques and norma...

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Bibliographic Details
Main Authors: Lei Jiang, Chuanji Hao, Zhenfu Li, Ping Zhang, Shizhong Wang, Sumin Yang, Fuling Wei, Jinqian Zhang
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Atherosclerosis
Endothelial nerosis cells (ECs)
EndMT (endothelial to mesenchymal transition)
Lipid rafts
Adiponectin receptor 2 (AdipoR2)
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218359213

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http://www.sciencedirect.com/science/article/pii/S0753332218359213

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