High Level of Serum and Cerebrospinal Fluid of Heparan Sulfate and Hyaluronic Acid Might Be a Biomarker of Severity of Neuromyelitis Optica

High Level of Serum and Cerebrospinal Fluid of Heparan Sulfate and Hyaluronic Acid Might Be a Biomarker of Severity of Neuromyelitis Optica

BackgroundNeuromyelitis optica (NMO), multiple sclerosis (MS) and autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy are idiopathic inflammatory demyelinating diseases (IIDDs) that mainly present as encephalomyelitis. Heparan sulfate (HS) and hyaluronic acid (HA) are two components of...

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Bibliographic Details
Main Authors: Qi Zhang, Shanshan Pei, Zheyi Zhou, Zhanhang Wang, Yu Peng, Jinyu Chen, Honghao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
glycocalyx
blood-brain barrier
heparan sulfate
hyaluronic acid
neuromyelitis optica
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.705536/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.705536/full

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