Polarizing the Neuron through Sustained Co-expression of Alternatively Spliced Isoforms

Alternative splicing (AS) is an important source of proteome diversity in eukaryotes. However, how this affects protein repertoires at a single-cell level remains an open question. Here, we show that many 3′-terminal exons are persistently co-expressed with their alternatives in mammalian neurons. I...

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Bibliographic Details
Main Authors: Karen Yap, Yixin Xiao, Brad A. Friedman, H. Shawn Je, Eugene V. Makeyev
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716304119