High density lipoproteins improve insulin sensitivity in high-fat diet-fed mice by suppressing hepatic inflammation[S]

High density lipoproteins improve insulin sensitivity in high-fat diet-fed mice by suppressing hepatic inflammation[S]

Obesity-induced liver inflammation can drive insulin resistance. HDL has anti-inflammatory properties, so we hypothesized that low levels of HDL would perpetuate inflammatory responses in the liver and that HDL treatment would suppress liver inflammation and insulin resistance. The aim of this study...

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Bibliographic Details
Main Authors: Kristine C. McGrath, Xiao Hong Li, Phillippa T. Whitworth, Robert Kasz, Joanne T. Tan, Susan V. McLennan, David S. Celermajer, Philip J. Barter, Kerry-Anne Rye, Alison K. Heather
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Journal of Lipid Research
Subjects:
insulin resistance
apolipoprotein AI
cellular signalling
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520376768

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520376768

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