An integrated approach to elucidate the intra-viral and viral-cellular protein interaction networks of a gamma-herpesvirus.

An integrated approach to elucidate the intra-viral and viral-cellular protein interaction networks of a gamma-herpesvirus.

Genome-wide yeast two-hybrid (Y2H) screens were conducted to elucidate the molecular functions of open reading frames (ORFs) encoded by murine γ-herpesvirus 68 (MHV-68). A library of 84 MHV-68 genes and gene fragments was generated in a Gateway entry plasmid and transferred to Y2H vectors. All possi...

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Bibliographic Details
Main Authors: Shaoying Lee, Lukasz Salwinski, Chaoying Zhang, Derrick Chu, Claire Sampankanpanich, Nichole A Reyes, Abbey Vangeloff, Fangfang Xing, Xudong Li, Ting-Ting Wu, Sudhir Sahasrabudhe, Hongyu Deng, Douglas J Lacount, Ren Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3197595?pdf=render

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http://europepmc.org/articles/PMC3197595?pdf=render

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