Temporal sensitivity of protein kinase a activation in late-phase long term potentiation.

Protein kinases play critical roles in learning and memory and in long term potentiation (LTP), a form of synaptic plasticity. The induction of late-phase LTP (L-LTP) in the CA1 region of the hippocampus requires several kinases, including CaMKII and PKA, which are activated by calcium-dependent sig...

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Bibliographic Details
Main Authors: MyungSook Kim, Ted Huang, Ted Abel, Kim T Blackwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2829045?pdf=render