Temporal sensitivity of protein kinase a activation in late-phase long term potentiation.
Protein kinases play critical roles in learning and memory and in long term potentiation (LTP), a form of synaptic plasticity. The induction of late-phase LTP (L-LTP) in the CA1 region of the hippocampus requires several kinases, including CaMKII and PKA, which are activated by calcium-dependent sig...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-02-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2829045?pdf=render |